1. Prolonged sleeplessness or insomnia; a state of being unable to sleep.
Usage: medical or formal; rare in modern English; more common in historical or medical texts

Examples

• The patient suffered from chronic agrypnia, unable to rest for more than an hour at a time.
• Medieval physicians documented cases of agrypnia in their medical records.
• Stress and anxiety can trigger agrypnia in susceptible individuals.
• The doctor prescribed medication to treat the patient's agrypnia.
• Prolonged agrypnia can have serious effects on physical and mental health.