1. showing or feeling active opposition or hostility toward someone or something
2. acting in opposition to or counteracting something
Usage: often used in scientific or technical contexts

Examples

• The two politicians had an antagonistic relationship throughout the campaign.
• Her antagonistic attitude made it difficult to work with her.
• The drug has an antagonistic effect on certain brain receptors.
• He became increasingly antagonistic toward his former business partner.
• The antagonistic forces within the organization led to its downfall.
• She gave him an antagonistic look across the courtroom.
• The two chemicals have antagonistic properties when mixed together.