1. Substances or drugs that block or inhibit the effects of oestrogen in the body, used especially in treating hormone-sensitive cancers.
Usage: medical/pharmaceutical; plural form; singular is antioestrogen; also spelled antiestrogens in U.S. English

Examples

• Antioestrogens are commonly prescribed to breast cancer patients whose tumours are oestrogen-sensitive.
• The research team studied how antioestrogens interact with oestrogen receptors in cancer cells.
• Tamoxifen is one of the most widely used antioestrogens in clinical practice.
• Doctors may recommend antioestrogens as part of hormone therapy to reduce cancer recurrence.
• New antioestrogens have been developed with fewer side effects than earlier generations.