noun
- A form of programmed cell death in which a cell actively participates in its own destruction, characterized by cell shrinkage, membrane blebbing, and fragmentation into membrane-bound particles.
Usage: technical; biology; medicine
Examples
- Apoptosis is essential for removing damaged cells and maintaining tissue homeostasis.
- Cancer cells often evade apoptosis, allowing them to survive and multiply uncontrollably.
- During development, apoptosis helps shape organs by eliminating excess cells.
- Researchers study apoptosis to understand how to trigger cell death in tumor cells.
- The immune system uses apoptosis to eliminate infected or abnormal cells.
- Defects in apoptosis pathways can lead to both cancer and neurodegenerative diseases.