1. A family of calcium-dependent proteases (enzymes) found in cells that break down proteins; involved in cell signaling, muscle contraction, and cell death.
Usage: technical; biology; plural form of calpain

Examples

• Calpains play a crucial role in regulating muscle contraction and relaxation.
• Researchers study calpains to understand how cells respond to calcium signals.
• Abnormal calpain activity has been linked to neurodegenerative diseases.
• The activation of calpains is tightly controlled by intracellular calcium levels.
• Scientists are investigating calpains as potential drug targets for treating muscle disorders.