noun
- An enzyme that catalyzes the addition or removal of a carboxyl group (-COOH) from a substrate molecule.
Usage: biochemistry; technical term
Examples
- Pyruvate carboxylase is an important enzyme in gluconeogenesis.
- The carboxylase enzyme catalyzes the conversion of pyruvate to oxaloacetate.
- Acetyl-CoA carboxylase plays a key role in fatty acid synthesis.
- Researchers studied how carboxylase activity affects metabolic pathways.
- The deficiency of certain carboxylases can lead to metabolic disorders.