1. An enzyme that catalyzes the production of prostaglandins and thromboxanes from arachidonic acid; important in inflammation, pain, and fever regulation.
Usage: technical; biochemistry; commonly abbreviated as COX

Examples

• Cyclooxygenase inhibitors are used to reduce inflammation and pain.
• The drug aspirin works by blocking cyclooxygenase enzymes.
• COX-2 selective inhibitors were developed to target specific cyclooxygenase isoforms.
• Cyclooxygenase plays a key role in the body's inflammatory response.
• Researchers study cyclooxygenase to understand how pain and fever develop.
• Nonsteroidal anti-inflammatory drugs inhibit cyclooxygenase activity.