1. the release of granules or granular contents from a cell, especially the discharge of chemical mediators from mast cells or basophils during an immune or allergic response
Usage: technical; biology/immunology

Examples

• Mast cell degranulation triggers the release of histamine during an allergic reaction.
• The degranulation of basophils leads to inflammation and itching in allergic responses.
• Researchers studied degranulation patterns to understand how immune cells respond to pathogens.
• Calcium influx is a key signal that initiates degranulation in immune cells.
• The drug was designed to inhibit degranulation and reduce allergic symptoms.