noun
- plural of demethylation; the chemical process of removing a methyl group (CH₃) from a molecule, commonly occurring in biochemistry and drug metabolism
Usage: technical; chemistry/biochemistry term; typically used in scientific and medical contexts
Examples
- Demethylations of DNA are important epigenetic modifications that regulate gene expression.
- The liver performs multiple demethylations during the metabolism of certain pharmaceuticals.
- Researchers studied the demethylations of histone proteins to understand chromatin remodeling.
- Aberrant demethylations can contribute to the development of cancer cells.
- Enzymatic demethylations play a crucial role in cellular signaling pathways.