1. causing someone to become mentally unstable or insane
2. disrupting the normal arrangement or functioning of something

Examples

• The constant noise was deranging his ability to concentrate.
• She worried that the stress was deranging her thoughts.
• The storm was deranging the carefully planned outdoor event.
• His illness was deranging his normal sleep patterns.
• The medication seemed to be deranging her memory.
• The construction work was deranging traffic flow throughout the city.