noun
- The chemical process of converting a compound into a derivative by introducing a new functional group or modifying an existing one.
Usage: technical; chemistry
Examples
- Derivatization of the sample improved its detection by gas chromatography.
- The researcher used derivatization to add a fluorescent tag to the protein.
- Silylation is a common derivatization method in organic synthesis.
- Derivatization can enhance the sensitivity of analytical measurements.
- The derivatization step was necessary before the compound could be analyzed by mass spectrometry.