adjective
- Of or relating to an enzyme that cleaves nucleic acid chains at internal sites rather than at the ends.
Usage: technical; biochemistry
Examples
- Endonucleolytic enzymes cut DNA in the middle of the strand.
- DNase I exhibits endonucleolytic activity on double-stranded DNA.
- The restriction enzyme has strong endonucleolytic properties.
- Endonucleolytic cleavage produces fragments of varying sizes.
- Researchers studied the endonucleolytic mechanism of the protease.