1. the state of being weakened or lacking physical or mental strength; exhaustion or debilitation
2. the act or process of weakening or sapping the strength or courage of someone or something

Examples

• The long illness caused a gradual enervation of his body and mind.
• Years of stress led to a complete enervation of her willpower.
• The heat and humidity contributed to a general enervation among the workers.
• The enervation of the team's morale was evident after the loss.
• Constant criticism resulted in the enervation of his confidence.
• The enervation caused by the disease made even simple tasks difficult.