noun
- A compound formed by the conjugation of glucuronic acid with another substance, especially a drug or toxin, in the body as part of metabolism or detoxification.
Usage: biochemistry; pharmacology
Examples
- The liver converts many drugs into glucuronides to make them easier to excrete.
- Acetaminophen is metabolized partly through glucuronidation in the liver.
- Glucuronides are water-soluble compounds that can be readily eliminated in urine.
- The formation of glucuronides is a major phase II detoxification pathway.
- Bilirubin glucuronides are produced when the liver processes hemoglobin breakdown products.