1. An enzyme that catalyzes the introduction or removal of supercoils in DNA, essential for DNA replication and transcription in bacteria.
Usage: biochemistry; molecular biology; also called DNA gyrase

Examples

• Gyrase is a critical enzyme in bacterial cells that manages DNA topology.
• The antibiotic fluoroquinolone works by inhibiting bacterial gyrase.
• Researchers studied how gyrase unwinds supercoiled DNA during replication.
• Gyrase activity is essential for the survival of most bacteria.
• The enzyme gyrase relieves tension in the DNA double helix.