1. Plural of gyrase; enzymes that catalyze the introduction or removal of supercoils in DNA, essential for DNA replication and transcription in bacteria.
Usage: biochemistry; molecular biology; technical term

Examples

• Bacterial gyrases are targets for many antibiotics used in clinical medicine.
• The gyrases in E. coli help manage the topological stress of DNA during replication.
• Fluoroquinolone antibiotics work by inhibiting bacterial gyrases.
• Different gyrases have been identified across various bacterial species.