1. A synthetic compound used as a ganglionic blocking agent in medicine, formerly employed to treat high blood pressure by blocking nerve impulses in autonomic ganglia.
Usage: medical/pharmacological term; largely historical; less commonly used in modern clinical practice

Examples

• Hexamethonium was developed in the 1950s as an experimental treatment for hypertension.
• The drug hexamethonium works by blocking acetylcholine receptors at the ganglia.
• Researchers studied hexamethonium to understand how ganglionic blocking agents affect blood pressure.
• Although hexamethonium proved effective, side effects limited its clinical use.