noun
- Plural of hypomorph; organisms or individuals that exhibit a hypomorphic mutation, resulting in reduced or weakened gene function compared to the wild type.
Usage: genetics; technical; biology
Examples
- The researchers studied hypomorphs to understand how partial loss of gene function affects development.
- Unlike null mutants, hypomorphs retain some level of protein activity.
- Hypomorphs are useful in genetic studies because they allow scientists to observe intermediate phenotypes.
- The hypomorphs showed reduced fertility compared to normal flies.
- By analyzing hypomorphs, the team identified which domains of the protein were essential for function.