1. A class of synthetic compounds derived from mecamylamine, used primarily as antihypertensive agents that block nicotinic acetylcholine receptors in the nervous system.
Usage: pharmaceutical/medical; plural form; technical term

Examples

• Mecamylamines were developed as ganglionic blocking agents to treat severe hypertension.
• The pharmacological properties of mecamylamines make them useful in research on nicotinic receptor antagonism.
• Clinical studies have examined the efficacy of mecamylamines in managing blood pressure in resistant cases.
• Mecamylamines work by blocking neural transmission at the ganglia, reducing sympathetic outflow.