1. relating to or denoting a mutation in DNA that results in a codon that codes for a different amino acid than the original
Usage: genetics; molecular biology

1. a mutation in which a single nucleotide change results in a codon that codes for a different amino acid
Usage: genetics; molecular biology

Examples

• A missense mutation can alter the protein's structure and function.
• The genetic test identified a missense variant in the BRCA1 gene.
• Missense mutations may have mild, moderate, or severe effects on protein activity.
• Scientists studied how the missense change affected enzyme efficiency.
• Not all missense mutations cause disease; some have no noticeable effect.