noun
- A dark pigment found in certain neurons of the brain, particularly in the substantia nigra, formed from the oxidation of dopamine.
Usage: technical; neuroscience
Examples
- Neuromelanin accumulates in dopamine-producing neurons throughout the lifespan.
- The loss of neuromelanin-containing cells in the substantia nigra is associated with Parkinson's disease.
- Researchers study neuromelanin levels to better understand neurodegenerative disorders.
- Neuromelanin gives certain brain regions a dark appearance under microscopy.
- The buildup of neuromelanin may contribute to oxidative stress in aging neurons.