1. a complete run or performance of a video game from start to finish
Usage: informal; gaming
2. a video or written guide showing how to complete a game, including strategies and solutions
Usage: informal; gaming
3. a rehearsal or trial performance of a play or theatrical production
Usage: theater

Examples

• I completed my first playthrough of the game in about 20 hours.
• She watched a playthrough online to figure out how to solve the puzzle.
• The director scheduled a full playthrough of the musical before opening night.
• His speedrun playthrough set a new world record.
• I'm starting a second playthrough on hard difficulty.
• The playthrough guide helped me find all the hidden collectibles.