1. a prediction or forecast of a future event, especially based on signs or omens
Usage: often implies prediction based on observation or interpretation of signs
2. the act or practice of predicting future events
Usage: refers to the process or method of making predictions

Examples

• The weather service issued a prognostication of heavy snow for the weekend.
• Ancient peoples used prognostication based on the movement of stars.
• Her prognostication about the company's future proved remarkably accurate.
• The economist's prognostication of a market downturn alarmed investors.
• Despite the prognostication of doom, the project succeeded beyond expectations.
• Medical prognostication helps doctors estimate a patient's recovery timeline.