noun
- A synthetic antimalarial and antiprotozoal drug used to treat malaria, toxoplasmosis, and certain parasitic infections.
Usage: medical; pharmaceutical; often used in combination with other drugs such as sulfadiazine
Examples
- Pyrimethamine is commonly prescribed to treat malaria in tropical regions.
- The doctor recommended pyrimethamine combined with sulfadiazine for the patient's toxoplasmosis.
- Pyrimethamine works by inhibiting the enzyme dihydrofolate reductase in parasites.
- Patients taking pyrimethamine may need regular blood tests to monitor for side effects.
- Pyrimethamine has been used for decades as a first-line antimalarial agent.