1. Plural of pyrimethamine; a class of antimalarial and antiprotozoal drugs that inhibit dihydrofolate reductase, used to treat malaria and certain parasitic infections.
Usage: medical/pharmaceutical term; typically used in clinical or research contexts

Examples

• Pyrimethamines are commonly prescribed in combination with sulfadiazine to treat toxoplasmosis.
• The resistance of malaria parasites to pyrimethamines has increased in some regions.
• Pyrimethamines work by blocking the synthesis of dihydrofolate in parasitic organisms.
• Doctors may use pyrimethamines as part of prophylactic treatment for certain at-risk populations.
• The efficacy of pyrimethamines depends on the specific parasite species and local drug resistance patterns.