1. hardened or thickened abnormally, especially of body tissue
Usage: medical
2. rigid or inflexible in attitude or approach
Usage: figurative

Examples

• The patient’s sclerosed arteries required immediate medical attention.
• Years of disease had left his liver tissue sclerosed and damaged.
• The sclerosed blood vessels showed signs of chronic inflammation.
• Her sclerosed thinking prevented her from considering new ideas.
• The company’s sclerosed management structure resisted all attempts at reform.
• His sclerosed attitudes made him unpopular with younger colleagues.