1. plural of substance; materials or matter with particular physical characteristics
2. chemical compounds, especially drugs or controlled materials
Usage: often in legal or medical contexts
3. things of real importance, value, or significance

Examples

• The laboratory tested various unknown substances found at the crime scene.
• Scientists are studying new substances that could revolutionize medicine.
• The athlete was banned for using illegal substances.
• These cleaning substances should be kept away from children.
• The treaty prohibits the production of certain hazardous substances.
• His speeches lacked substances and failed to address real issues.
• The report contained substances that could influence policy decisions.