1. most full of twists and turns; most winding or curved
Usage: superlative form of twisty
2. most complex or confusing; having the most unexpected turns or complications
Usage: figurative use

Examples

• The mountain road was the twistiest path I had ever driven.
• This is the twistiest section of the river, with sharp bends every few hundred yards.
• The mystery novel had the twistiest plot, with surprises on every page.
• Among all the hiking trails, this one has the twistiest route through the forest.
• The twistiest part of the maze took us twenty minutes to navigate.
• Her explanation was the twistiest I’d ever heard, full of contradictions and detours.